Sobrecarga cognitiva y emocional como fenotipos diferenciados en cuidadores de Alzheimer
DOI:
https://doi.org/10.71112/0mj0tk97Palabras clave:
enfermedad de Alzheimer, sobrecarga del cuidador, funcionamiento ejecutivo, Trail Making Test, sobrecarga cognitiva, perfiles de cuidadoresResumen
Introducción: El cuidado informal de personas con Alzheimer genera demandas que afectan la salud del cuidador de formas poco evaluadas.
Objetivo: Identificar perfiles de sobrecarga del cuidador según carga, estrés y función ejecutiva, y el aporte de esta última.
Métodos: Estudio transversal en 84 cuidadores informales de personas con Alzheimer en Punta Arenas, Chile, evaluados con la Entrevista de Sobrecarga de Zarit, el Cuestionario de Afrontamiento del Estrés, el Trail Making Test y el Índice de AVD Instrumentales.
Resultados: Se identificaron tres perfiles —baja sobrecarga, sobrecarga cognitiva (alta carga, bajo estrés, TMT-B deteriorado) y sobrecarga emocional (alta carga, estrés elevado)—, con diferencias significativas en sobrecarga (p < ,001). El TMT-B explicó un 54% de varianza adicional más allá del estrés.
Conclusiones: La sobrecarga no se reduce a un perfil emocional único: algunos cuidadores muestran alta carga con bajo estrés, pero compromiso ejecutivo, lo que respalda evaluar también la función ejecutiva.
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Allen, A. P., Curran, E. A., Duggan, Á., Cryan, J. F., Ní Chorcoráin, A., Dinan, T. G., Molloy, D. W., Kearney, P. M., & Clarke, G. (2017). A systematic review of the psychobiological burden of informal caregiving for patients with dementia: focus on cognitive and biological markers of chronic stress. Neuroscience & Biobehavioral Reviews, 73, 123-164. https://doi.org/10.1016/j.neubiorev.2016.12.006
Altintas, E., Luyat, M., Gallouj, K., Hülür, G., & El Haj, M. (2024). Burden of family caregivers in Alzheimer's disease: the role of caregivers' perception of cognitive impairment. Applied Neuropsychology: Adult. Publicación electrónica anticipada. https://doi.org/10.1080/23279095.2024.2367102
Alzheimer's Association. (2021). 2021 Alzheimer's disease facts and figures. Alzheimer's & Dementia, 17(3), 327-406. https://doi.org/10.1002/alz.12328
Arango-Lasprilla, J. C., Rivera, D., Aguayo, A., Rodríguez, W., Garza, M. T., Saracho, C. P., et al. (2015). Trail Making Test: normative data for the Latin American Spanish speaking adult population. NeuroRehabilitation, 37(4), 639-661. https://doi.org/10.3233/NRE-151284
Brito, L., Cepa, B., Brito, C., Leite, Â., & Pereira, M. G. (2025). Risk assessment profiles for caregiver burden in family caregivers of persons living with Alzheimer's disease: an exploratory study with machine learning. European Journal of Investigation in Health, Psychology and Education, 15(3), 41. https://doi.org/10.3390/ejihpe15030041
Cascella Carbó, G. F., & García-Orrellán, R. (2020). Burden and gender inequalities around informal care. Investigación y Educación en Enfermería, 38(1), e10. https://doi.org/10.17533/udea.iee.v38n1e10
Del-Pino-Casado, R., Priego-Cubero, E., López-Martínez, C., & Orgeta, V. (2021). Subjective caregiver burden and anxiety in informal caregivers: a systematic review and meta-analysis. PLoS ONE, 16(3), e0247143. https://doi.org/10.1371/journal.pone.0247143
Domínguez-Vergara, J., Santa-Cruz-Espinoza, H., & Chávez-Ventura, G. (2023). Zarit Caregiver Burden Interview: psychometric properties in family caregivers of people with intellectual disabilities. European Journal of Investigation in Health, Psychology and Education, 13(2), 391-402. https://doi.org/10.3390/ejihpe13020029
Du, C., Camacho, M. R., Goldfeder, R. L., et al. (2022). Digitally generated Trail Making Test data: analysis using hidden Markov modeling. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 14(1), e12292. https://doi.org/10.1002/dad2.12292
Frias, C. E., Cabrera, E., & Zabalegui, A. (2020). Informal caregivers' roles in dementia: the impact on their quality of life. Life, 10(11), 251. https://doi.org/10.3390/life10110251
Jütten, L. H., Mark, R. E., & Sitskoorn, M. M. (2020). Episodic memory and executive functioning in informal dementia caregivers. Aging & Mental Health, 24(10), 1681-1689. https://doi.org/10.1080/13607863.2019.1617242
Kang, H. S., Myung, W., Na, D. L., Kim, S. Y., Lee, J. H., Han, S. H., Choi, S. H., Kim, S. Y., Kim, S., & Kim, D. K. (2014). Factors associated with caregiver burden in patients with Alzheimer's disease. Psychiatry Investigation, 11(2), 152-159. https://doi.org/10.4306/pi.2014.11.2.152
Lawton, M. P., & Brody, E. M. (1969). Assessment of older people: self-maintaining and instrumental activities of daily living. The Gerontologist, 9(3, Pt. 1), 179-186. https://doi.org/10.1093/geront/9.3_Part_1.179
Ma, M., Dorstyn, D., Ward, L., & Prentice, S. (2018). Alzheimer's disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls. Aging & Mental Health, 22(11), 1395-1405. https://doi.org/10.1080/13607863.2017.1370689
Mallya, S., & Fiocco, A. J. (2018). Impact of informal caregiving on cognitive function and well-being in Canada. International Psychogeriatrics, 30(7), 1049-1055. https://doi.org/10.1017/S1041610217002605
Milligan, G. W., & Cooper, M. C. (1985). An examination of procedures for determining the number of clusters in a data set. Psychometrika, 50(2), 159-179. https://doi.org/10.1007/BF02294245
Mohammed, A., Williams, I. C., & Mattos, M. K. (2026). Impact of formal services on care recipient behavioral symptoms of dementia and caregiver burden: a scoping review. Journal of Applied Gerontology. Publicación electrónica anticipada. https://doi.org/10.1177/07334648261474973
National Library of Medicine. (s.f.). Mental fatigue. MeSH Browser. Recuperado el 1 de junio de 2026, de https://meshb.nlm.nih.gov/record/ui?ui=D005222
Nichols, E., Steinmetz, J. D., Vollset, S. E., Oria, M., Baumann, M., Bhatt, S., et al. (2022). Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. The Lancet Public Health, 7(2), e105-e125. https://doi.org/10.1016/S2468-2667(21)00249-8
Pinyopornpanish, K., Soontornpun, A., Wongpakaran, T., Wongpakaran, N., Tanprawate, S., Nadsasarn, A., et al. (2022). Impact of behavioral and psychological symptoms of Alzheimer's disease on caregiver outcomes. Scientific Reports, 12(1), 14138. https://doi.org/10.1038/s41598-022-18470-8
Pinyopornpanish, M., Pinyopornpanish, K., Soontornpun, A., Tanprawate, S., Nadsasarn, A., Wongpakaran, N., et al. (2021). Perceived stress and depressive symptoms not neuropsychiatric symptoms predict caregiver burden in Alzheimer's disease: a cross-sectional study. BMC Geriatrics, 21(1), 180. https://doi.org/10.1186/s12877-021-02136-7
Reitan, R. M. (1958). Validity of the Trail Making Test as an indicator of organic brain damage. Perceptual and Motor Skills, 8(3), 271-276.
Ruisoto, P., Contador, I., Fernández-Calvo, B., Serra, L., Jenaro, C., Flores, N., et al. (2020). Mediating effect of social support on the relationship between resilience and burden in caregivers of people with dementia. Archives of Gerontology and Geriatrics, 86, 103952. https://doi.org/10.1016/j.archger.2019.103952
Sandín, B., & Chorot, P. (2003). Cuestionario de Afrontamiento del Estrés (CAE): desarrollo y validación preliminar. Revista de Psicopatología y Psicología Clínica, 8(1), 39-54. https://doi.org/10.5944/rppc.vol.8.num.1.2003.3941
Sołtys, A., & Tyburski, E. (2020). Predictors of mental health problems in formal and informal caregivers of patients with Alzheimer's disease. BMC Psychiatry, 20(1), 435. https://doi.org/10.1186/s12888-020-02822-7
Tatomirescu, L., Prada, G., Glavce, C., David-Rus, R., & Borosanu, A. (2025). Well-being profiles of family caregivers of patients with dementia from Romania: a latent profile analysis. Cureus, 17(4), e83103. https://doi.org/10.7759/cureus.83103
Van Den Kieboom, R., Snaphaan, L., Mark, R., & Bongers, I. (2020). The trajectory of caregiver burden and risk factors in dementia progression: a systematic review. Journal of Alzheimer's Disease, 77(3), 1107-1115. https://doi.org/10.3233/JAD-200647
Wisconsin Alzheimer's Institute. (2021). Zarit caregiver burden assessment instruments. University of Wisconsin School of Medicine and Public Health. https://www.wai.wisc.edu/
Yin, X., Xie, Q., Huang, L., et al. (2021). Assessment of the psychological burden among family caregivers of people living with Alzheimer's disease using the Zarit Burden Interview. Journal of Alzheimer's Disease, 82(1), 285-291. https://doi.org/10.3233/JAD-210025
Yuan, Q., Tan, G. T. H., Wang, P., Devi, F., Goveas, R., Magadi, H., et al. (2021). Combining a variable-centered and a person-centered analytical approach to caregiving burden - a holistic approach. BMC Geriatrics, 21(1), 286. https://doi.org/10.1186/s12877-021-02238-2
Zarit, S. H., Reever, K. E., & Bach-Peterson, J. (1980). Relatives of the impaired elderly: correlates of feelings of burden. The Gerontologist, 20(6), 649-655. https://doi.org/10.1093/geront/20.6.649
Zygouri, I., Cowdell, F., Ploumis, A., Gouva, M., & Mantzoukas, S. (2021). Gendered experiences of providing informal care for older people: a systematic review and thematic synthesis. BMC Health Services Research, 21(1), 730. https://doi.org/10.1186/s12913-021-06736-2
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Derechos de autor 2026 Fernanda Tapia Acevedo, Jonathan Lühr Henríquez, Wolfrang Lühr Henríquez, Karena Espinoza Saavedra, Antonia Lavanchy Verdugo (Autor/a)

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.






