Impact of central venous catheter-associated bacteremia in critically ill neutropenic and non-neutropenic cancer patients in the adult intensive care unit of the Dr. Julio Villacreses Colmont SOLCA Manabí Cancer Hospital
DOI:
https://doi.org/10.71112/2xxmwr04Keywords:
central venous catheter bloodstream infection, neutropenia, critically ill cancer patients, intensive care unitAbstract
Central venous catheter-associated bloodstream infection (CLABSI) represents one of the most significant healthcare-associated infections in critically ill cancer patients. The aim of this study was to analyze the clinical impact of CLABSI in neutropenic and non-neutropenic oncologic patients admitted to the Adult Intensive Care Unit of the Dr. Julio Villacreses Colmont Oncology Hospital – SOLCA Manabí. A quantitative, observational, and analytical study with a retrospective cohort design was conducted between January 2024 and June 2025. The sample included 120 patients with confirmed CLABSI. The findings showed high rates of septic shock, multiple organ failure, and hospital mortality. Neutropenic patients presented higher mortality rates and longer ICU stays compared with non-neutropenic patients. Multivariable analysis identified neutropenia, mechanical ventilation, and vasopressor use as independent predictors of hospital mortality. These results highlight the need to strengthen infection prevention strategies, epidemiological surveillance, and timely management of catheter-related bloodstream infections in critically ill oncologic patients.
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Copyright (c) 2026 Jimmy Manuel Quijije Gaibor, Edwin Antonio Bravo Loor, Luiggy Marcelo Zambrano Pionce, Genesis Shirley Guzman Espinoza, Lady Katherine Tortorelli García (Autor/a)
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